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Experts stop short of recommending zinc oxide at each diaper change unless your baby is prone to rashes and redness. Ask yourself: Are you changing baby’s diaper as soon as it’s wet or soiled? Are you checking baby’s diaper shortly after each feeding? Is baby using at least 8-12 diapers daily? If you’re doing these things and rash remains persistent, follow up with baby’s healthcare provider explore what may be causing persistent diaper rash.Ask Our Nurses